Design

The class <code>Design</code> represents and stores information for the Design.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

Design function

<dl><dt>name</dt>
<dd>A string giving the name of the design.</dd>
<dt>size</dt>
<dd>A integer giving the size of the design.</dd>
<dt>arms</dt>
<dd>A list giving the arms of the design.</dd>
<dt>evaluationArms</dt>
<dd>A list giving the valuation of the arms of the design.</dd>
<dt>numberOfArms</dt>
<dd>A integer giving the number of arms.</dd>
<dt>fim</dt>
<dd>A object <code>Fim</code> giving the Fim of the design.</dd></dl>

Arguments

Design — Design

<dl>

<dt>name</dt>
<dd>A string giving the name of the design.</dd>


<dt>size</dt>
<dd>A integer giving the size of the design.</dd>


<dt>arms</dt>
<dd>A list giving the arms of the design.</dd>


<dt>evaluationArms</dt>
<dd>A list giving the valuation of the arms of the design.</dd>


<dt>numberOfArms</dt>
<dd>A integer giving the number of arms.</dd>


<dt>fim</dt>
<dd>A object <code>Fim</code> giving the Fim of the design.</dd>

</dl>

Design: Design

Description

Usage

Arguments

Details