ModelParameter

The class <code>ModelParameter</code> is used to defined the model parameters.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

ModelParameter function

<dl><dt>name</dt>
<dd>A string giving the name of the parameter.</dd>
<dt>distribution</dt>
<dd>A string giving the distribution of the parameter.</dd>
<dt>fixedMu</dt>
<dd>A Boolean setting TRUE/FALSE if the mu is estimated or not.</dd>
<dt>fixedOmega</dt>
<dd>A Boolean setting TRUE/FALSE if the omega is estimated or not.</dd></dl>

Arguments

ModelParameter — ModelParameter

<dl>

<dt>name</dt>
<dd>A string giving the name of the parameter.</dd>


<dt>distribution</dt>
<dd>A string giving the distribution of the parameter.</dd>


<dt>fixedMu</dt>
<dd>A Boolean setting TRUE/FALSE if the mu is estimated or not.</dd>


<dt>fixedOmega</dt>
<dd>A Boolean setting TRUE/FALSE if the omega is estimated or not.</dd>

</dl>

ModelParameter: ModelParameter

Description

Usage

Arguments

Details