defineModelWrapper

defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver
defineModelWrapper: define the model wrapper for the ode solver

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

defineModelWrapper function

<dl><dt>model</dt>
<dd>An object of class <code>ModelODEInfusionDoseInEquation</code> that defines the model.</dd>
<dt>evaluation</dt>
<dd>An object of class Evaluation that defines the evaluation</dd></dl>

Arguments

defineModelWrapper: define the model wrapper for the ode solver — defineModelWrapper

<dl>

<dt>model</dt>
<dd>An object of class <code>ModelODEInfusionDoseInEquation</code> that defines the model.</dd>


<dt>evaluation</dt>
<dd>An object of class Evaluation that defines the evaluation</dd>

</dl>

defineModelWrapper: defineModelWrapper: define the model wrapper for the ode solver

Description

Value

Arguments