definePKPDModel

definePKPDModel: define a PKPD model from library of model
definePKPDModel: define a PKPD model from library of model
definePKPDModel ModelAnalyticInfusion, ModelAnalytic
definePKPDModel ModelAnalyticInfusion, ModelODE
definePKPDModel
definePKPDModel
definePKPDModel
definePKPDModel: define a PKPD model from library of model

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

definePKPDModel function

<dl><dt>pkModel</dt>
<dd>An object of class <code>ModelODE</code> that defines the PD model.</dd>
<dt>pfimproject</dt>
<dd>An object of class <code>PFIMProject</code> that defines the pfimproject.</dd></dl>

Arguments

definePKPDModel:  define a PKPD model from library of model — definePKPDModel

<dl>

<dt>pkModel</dt>
<dd>An object of class <code>ModelODE</code> that defines the PD model.</dd>


<dt>pfimproject</dt>
<dd>An object of class <code>PFIMProject</code> that defines the pfimproject.</dd>

</dl>

definePKPDModel: definePKPDModel: define a PKPD model from library of model

Description

Arguments