evaluateArm

evaluateArm: evaluation of the model with the arm parameters.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

evaluateArm function

<dl><dt>arm</dt>
<dd>A object of class <code>Arm</code> giving the arm.</dd>
<dt>model</dt>
<dd>A object of class <code>Model</code> giving the model.</dd>
<dt>fim</dt>
<dd>A object of class <code>Fim</code> giving the fim.</dd></dl>

Arguments

evaluateArm: evaluation of the model with the arm parameters. — evaluateArm

<dl>

<dt>arm</dt>
<dd>A object of class <code>Arm</code> giving the arm.</dd>


<dt>model</dt>
<dd>A object of class <code>Model</code> giving the model.</dd>


<dt>fim</dt>
<dd>A object of class <code>Fim</code> giving the fim.</dd>

</dl>

evaluateArm: evaluateArm: evaluation of the model with the arm parameters.

Description

Value

Arguments