generateSamplingTimesCombination

generateSamplingTimesCombination: generate the combination for the samplings.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

generateSamplingTimesCombination function

<dl><dt>design</dt>
<dd>An object <code>Design</code> giving the design.</dd></dl>

Arguments

generateSamplingTimesCombination: generate the combination for the samplings. — generateSamplingTimesCombination

<dl>

<dt>design</dt>
<dd>An object <code>Design</code> giving the design.</dd>

</dl>

generateSamplingTimesCombination: generateSamplingTimesCombination: generate the combination for the samplings.

Description

Value

Arguments