getArmConstraints

getArmConstraints: get the administration and sampling time constraints for the MultiplicativeAlgorithm.
getArmConstraints: get the administration and sampling time constraints for the FedorovWynnAlgorithm.
getArmConstraints: get the administration and sampling time constraints for the SimplexAlgorithm.
getArmConstraints: get the administration and sampling time constraints for the PSOAlgorithm.
getArmConstraints: get the administration and sampling time constraints for the PGBOAlgorithm.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

getArmConstraints function

<dl><dt>arm</dt>
<dd>A object of class <code>Arm</code> giving the arm.</dd>
<dt>optimizationAlgorithm</dt>
<dd>A object of class <code>Optimization</code> giving the optimization algorithm.</dd></dl>

Arguments

getArmConstraints: get the administration and sampling time constraints for the MultiplicativeAlgorithm. — getArmConstraints

<dl>

<dt>arm</dt>
<dd>A object of class <code>Arm</code> giving the arm.</dd>


<dt>optimizationAlgorithm</dt>
<dd>A object of class <code>Optimization</code> giving the optimization algorithm.</dd>

</dl>

getArmConstraints: getArmConstraints: get the administration and sampling time constraints for the MultiplicativeAlgorithm.

Description

Value

Arguments