getFisherMatrix

getFisherMatrix: display the Fisher matrix components
getFisherMatrix: display the Fisher matrix components

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

getFisherMatrix function

<dl><dt>evaluation</dt>
<dd>An object <code>Evaluation</code> giving the evaluation to be run.</dd></dl>

Arguments

getFisherMatrix: display the Fisher matrix components — getFisherMatrix

<dl>

<dt>evaluation</dt>
<dd>An object <code>Evaluation</code> giving the evaluation to be run.</dd>

</dl>

getFisherMatrix: getFisherMatrix: display the Fisher matrix components

Description

Value

Arguments