optimizeDesign

Optimization PGBOAlgorithm
Optimization PSOAlgorithm
Optimization SimplexAlgorithm
Optimization FedorovWynnAlgorithm
Optimization MultiplicativeAlgorithm

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

optimizeDesign function

<dl><dt>optimizationObject</dt>
<dd>A object <code>Optimization</code>.</dd>
<dt>optimizationAlgorithm</dt>
<dd>A object <code>MultiplicativeAlgorithm</code>.</dd></dl>

Arguments

Optimization PGBOAlgorithm — optimizeDesign

<dl>

<dt>optimizationObject</dt>
<dd>A object <code>Optimization</code>.</dd>


<dt>optimizationAlgorithm</dt>
<dd>A object <code>MultiplicativeAlgorithm</code>.</dd>

</dl>

optimizeDesign: Optimization PGBOAlgorithm

Description

Value

Arguments