setSamplingConstraintForOptimization

setSamplingConstraintForOptimization: set the sampling time constraints for an arm for the design optimization.

Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to
Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>,
Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>,
Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>,
Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>,
Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and
Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.

Romain Leroux

PFIM

Population Fisher Information Matrix

France Mentré

Jérémy Seurat

setSamplingConstraintForOptimization function

<dl><dt>design</dt>
<dd>An object <code>Design</code> giving the design.</dd></dl>

Arguments

setSamplingConstraintForOptimization: set the sampling time constraints for an arm for the design optimization. — setSamplingConstraintForOptimization

<dl>

<dt>design</dt>
<dd>An object <code>Design</code> giving the design.</dd>

</dl>

setSamplingConstraintForOptimization: setSamplingConstraintForOptimization: set the sampling time constraints for an arm for the design optimization.

Description

Value

Arguments