pk.calc.tmax

Input restrictions are:<ol>
<li>the <code>conc</code> and <code>time</code> must be the same length,</li>
<li>the <code>time</code> may have no NAs,</li>
</ol><code>NA</code> will be returned if:<ol>
<li>the length of <code>conc</code> and <code>time</code> is 0</li>
<li>all <code>conc</code> is 0 or <code>NA</code></li>
</ol>

Compute standard Non-Compartmental Analysis (NCA) parameters for
typical pharmacokinetic analyses and summarize them.

Bill Denney

PKNCA

Perform Pharmacokinetic Non-Compartmental Analysis

Clare Buckeridge

Sridhar Duvvuri

pk.calc.tmax function

<dl><dt>conc</dt>
<dd>Concentration measured</dd>
<dt>time</dt>
<dd>Time of concentration measurement</dd>
<dt>options</dt>
<dd>List of changes to the default
<code>PKNCA.options</code> for calculations.</dd>
<dt>first.tmax</dt>
<dd>If there is more than time that matches the
maximum concentration, should the first be considered as Tmax? If
not, then the last is considered Tmax.</dd>
<dt>check</dt>
<dd>Run <code>check.conc.time</code>?</dd></dl>

Arguments

Determine time of maximum observed PK concentration — pk.calc.tmax

<dl>

<dt>conc</dt>
<dd>Concentration measured</dd>


<dt>time</dt>
<dd>Time of concentration measurement</dd>


<dt>options</dt>
<dd>List of changes to the default
<code>PKNCA.options</code> for calculations.</dd>


<dt>first.tmax</dt>
<dd>If there is more than time that matches the
maximum concentration, should the first be considered as Tmax? If
not, then the last is considered Tmax.</dd>


<dt>check</dt>
<dd>Run <code>check.conc.time</code>?</dd>

</dl>

pk.calc.tmax: Determine time of maximum observed PK concentration

Description

Usage

Value

Arguments