Calculate the volume of distribution (Vd) or observed volume of distribution (Vd/F)
pk.calc.vd(dose, aucinf, lambda.z)
The observed volume of distribution
One or more doses given during an interval
Area under the curve to infinity (either predicted or observed).
Elimination rate constant
vd is dose/(aucinf * lambda.z)
.
If dose
is the same length as the other inputs, then
the output will be the same length as all of the inputs; the
function assumes that you are calculating for multiple intervals
simultaneously. If the inputs other than dose
are scalars
and dose
is a vector, then the function assumes multiple
doses were given in a single interval, and the sum of the
dose
s will be used for the calculation.