pk.calc.time_above

Interpolation is performed aligning with <code>PKNCA.options("auc.method")</code>.
Extrapolation outside of the measured times is not yet implemented. The
<code>method</code> may be changed by giving a named <code>method</code> argument, as
well.

Compute standard Non-Compartmental Analysis (NCA) parameters for
typical pharmacokinetic analyses and summarize them.

Bill Denney

PKNCA

Perform Pharmacokinetic Non-Compartmental Analysis

Clare Buckeridge

Sridhar Duvvuri

pk.calc.time_above function

<dl><dt>conc</dt>
<dd>Concentration measured</dd>
<dt>time</dt>
<dd>Time of concentration measurement (must be monotonically
increasing and the same length as the concentration data)</dd>
<dt>conc_above</dt>
<dd>The concentration to be above</dd>
<dt>...</dt>
<dd>Extra arguments. Currently, the only extra argument that is used
is <code>method</code> as described in the details section.</dd>
<dt>options</dt>
<dd>List of changes to the default <code>PKNCA.options</code> for
calculations.</dd>
<dt>check</dt>
<dd>Run <code>check.conc.time</code>, <code>clean.conc.blq</code>,
and <code>clean.conc.na</code>?</dd></dl>

Arguments

Determine time at or above a set value — pk.calc.time_above

<dl>

<dt>conc</dt>
<dd>Concentration measured</dd>


<dt>time</dt>
<dd>Time of concentration measurement (must be monotonically
increasing and the same length as the concentration data)</dd>


<dt>conc_above</dt>
<dd>The concentration to be above</dd>


<dt>...</dt>
<dd>Extra arguments. Currently, the only extra argument that is used
is <code>method</code> as described in the details section.</dd>


<dt>options</dt>
<dd>List of changes to the default <code>PKNCA.options</code> for
calculations.</dd>


<dt>check</dt>
<dd>Run <code>check.conc.time</code>, <code>clean.conc.blq</code>,
and <code>clean.conc.na</code>?</dd>

</dl>

pk.calc.time_above: Determine time at or above a set value

Description

Usage

Value

Arguments

Details