interp_extrap_conc_method

interpolate_conc_linear

interpolate_conc_log

extrapolate_conc_lambdaz

Interpolate or extrapolate concentrations using the provided method

internal

Compute standard Non-Compartmental Analysis (NCA) parameters for
typical pharmacokinetic analyses and summarize them.

Bill Denney

PKNCA

Perform Pharmacokinetic Non-Compartmental Analysis

Clare Buckeridge

Sridhar Duvvuri

interp_extrap_conc_method function

<dl><dt>conc_1, conc_2</dt>
<dd>The concentration at time1 and time2</dd>
<dt>time_1, time_2</dt>
<dd>The time value associated with conc1 and conc2</dd>
<dt>time_out</dt>
<dd>Time when interpolation is requested</dd>
<dt>clast</dt>
<dd>The concentration at the last time above the lower LOQ</dd>
<dt>lambda.z</dt>
<dd>The elimination rate (in units of inverse time) for
extrapolation</dd>
<dt>tlast</dt>
<dd>The time of the last concentration above the lower limit of
quantification (LOQ)</dd></dl>

Arguments

Interpolate or extrapolate concentrations using the provided method — interp_extrap_conc_method

<dl>

<dt>conc_1, conc_2</dt>
<dd>The concentration at time1 and time2</dd>


<dt>time_1, time_2</dt>
<dd>The time value associated with conc1 and conc2</dd>


<dt>time_out</dt>
<dd>Time when interpolation is requested</dd>


<dt>clast</dt>
<dd>The concentration at the last time above the lower LOQ</dd>


<dt>lambda.z</dt>
<dd>The elimination rate (in units of inverse time) for
extrapolation</dd>


<dt>tlast</dt>
<dd>The time of the last concentration above the lower limit of
quantification (LOQ)</dd>

</dl>

interp_extrap_conc_method: Interpolate or extrapolate concentrations using the provided method

Description

Usage

Value

Arguments