Calculate the mean residence time (MRT) for single-dose data or linear multiple-dose data.
pk.calc.mrt(auc, aumc)pk.calc.mrt.iv(auc, aumc, duration.dose)
the numeric value of the mean residence time
the AUC from 0 to infinity or 0 to tau
the AUMC from 0 to infinity or 0 to tau
The duration of the dose (usually an infusion duration for an IV infusion)
pk.calc.mrt.iv()
: MRT for an IV infusion
mrt is aumc/auc - duration.dose/2
where duration.dose = 0
for oral administration.
pk.calc.mrt.md()