PKNCA (version 0.9.4)

pk.tss.data.prep: Clean up the time to steady-state parameters and return a data frame for use by the tss calculators.

Description

Clean up the time to steady-state parameters and return a data frame for use by the tss calculators.

Usage

pk.tss.data.prep(
  conc,
  time,
  subject,
  treatment,
  subject.dosing,
  time.dosing,
  options = list(),
  conc.blq = NULL,
  conc.na = NULL,
  check = TRUE,
  ...
)

Arguments

conc

Concentration measured

time

Time of concentration measurement

subject

Subject identifiers (used as a random effect in the model)

treatment

Treatment description (if missing, all subjects are assumed to be on the same treatment)

subject.dosing

Subject number for dosing

time.dosing

Time of dosing

options

List of changes to the default PKNCA.options for calculations.

conc.blq

See clean.conc.blq

conc.na

See clean.conc.na

check

Run check.conc.time?

…

Discarded inputs to allow generic calls between tss methods.

Value

a data frame with columns for concentration, time, subject, and treatment.