pk.calc.time_above

conc

Time of concentration measurement (must be monotonically
increasing and the same length as the concentration data)

time

The concentration to be above (if missing will use
<code>PKNCA.choose.option(name="conc_above", value=conc_above, options=options)</code>)

conc_above

The method for integration (either 'lin up/log down' or
'linear')

method

List of changes to the default <code><a rd-options="" href="/link/PKNCA.options?package=PKNCA&version=0.9.5" data-mini-rdoc="PKNCA::PKNCA.options">PKNCA.options</a></code> for
calculations.

options

Run <code><a rd-options="" href="/link/check.conc.time?package=PKNCA&version=0.9.5" data-mini-rdoc="PKNCA::check.conc.time">check.conc.time</a></code>, <code><a rd-options="" href="/link/clean.conc.blq?package=PKNCA&version=0.9.5" data-mini-rdoc="PKNCA::clean.conc.blq">clean.conc.blq</a></code>,
and <code><a rd-options="" href="/link/clean.conc.na?package=PKNCA&version=0.9.5" data-mini-rdoc="PKNCA::clean.conc.na">clean.conc.na</a></code>?

check

Interpolation is performed aligning with <code>PKNCA.options("auc.method")</code>.
Extrapolation outside of the measured times is not yet implemented.

Compute standard Non-Compartmental Analysis (NCA) parameters for
typical pharmacokinetic analyses and summarize them.

Bill Denney

PKNCA

Perform Pharmacokinetic Non-Compartmental Analysis

Clare Buckeridge

Sridhar Duvvuri

pk.calc.time_above function

<dl><dt>conc</dt>
<dd>Concentration measured</dd>
<dt>time</dt>
<dd>Time of concentration measurement (must be monotonically
increasing and the same length as the concentration data)</dd>
<dt>conc_above</dt>
<dd>The concentration to be above (if missing will use
<code>PKNCA.choose.option(name="conc_above", value=conc_above, options=options)</code>)</dd>
<dt>method</dt>
<dd>The method for integration (either 'lin up/log down' or
'linear')</dd>
<dt>options</dt>
<dd>List of changes to the default <code>PKNCA.options</code> for
calculations.</dd>
<dt>check</dt>
<dd>Run <code>check.conc.time</code>, <code>clean.conc.blq</code>,
and <code>clean.conc.na</code>?</dd></dl>

Arguments

Determine time at or above a set value — pk.calc.time_above

<dl>

<dt>conc</dt>
<dd>Concentration measured</dd>


<dt>time</dt>
<dd>Time of concentration measurement (must be monotonically
increasing and the same length as the concentration data)</dd>


<dt>conc_above</dt>
<dd>The concentration to be above (if missing will use
<code>PKNCA.choose.option(name="conc_above", value=conc_above, options=options)</code>)</dd>


<dt>method</dt>
<dd>The method for integration (either 'lin up/log down' or
'linear')</dd>


<dt>options</dt>
<dd>List of changes to the default <code>PKNCA.options</code> for
calculations.</dd>


<dt>check</dt>
<dd>Run <code>check.conc.time</code>, <code>clean.conc.blq</code>,
and <code>clean.conc.na</code>?</dd>

</dl>

pk.calc.time_above: Determine time at or above a set value

Description

Usage

Value

Arguments