PKPDindex_data

Example dataset for Emax model fitting.

datasets

Fits Emax models to pharmacokinetic/pharmacodynamic (PK/PD) data, estimate key parameters, and visualise model fits for multiple PK/PD indices. Methods are described in Macdougall J (2006) <doi:10.1007/0-387-33706-7_9>, Spiess AN, Neumeyer N (2010) <doi:10.1186/1471-2210-10-6>, and Burnham KP, Anderson DR (2004) <doi:10.1177/0049124104268644>.

Najla Alabdulkarim

PKPDindex

Optimal PK/PD Index Finder

Joseph F Standing

PKPDindex_data function

A data frame with 20 rows and 4 columns:<dl>
<dt>auc_mic</dt>
<dd>Area under the concentration-time curve (numeric)</dd><dt>cmax_mic</dt>
<dd>Maximum concentration of the drug (numeric)</dd><dt>t_mic</dt>
<dd>Time above minimum inhibitory concentration (numeric)</dd><dt>response</dt>
<dd>Observed drug response (numeric; Delta log10 CFU/ml)</dd>
</dl>

Format

PKPDindex_data — PKPDindex_data

A data frame with 20 rows and 4 columns:<dl>
<dt>auc_mic</dt>
<dd>Area under the concentration-time curve (numeric)</dd>

<dt>cmax_mic</dt>
<dd>Maximum concentration of the drug (numeric)</dd>

<dt>t_mic</dt>
<dd>Time above minimum inhibitory concentration (numeric)</dd>

<dt>response</dt>
<dd>Observed drug response (numeric; Delta log10 CFU/ml)</dd>


</dl>

PKPDindex_data: PKPDindex_data

Description

Usage

Arguments

Format

Details

Examples