ThreeCompIVinfusionMetab

3-compartment IV infusion with first-order metabolite formation

internal

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).

Ron Keizer

PKPDsim

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Jasmine Hughes

Dominic Tong

Kara Woo

Jordan Brooks

InsightRX 

ThreeCompIVinfusionMetab function

<dl><dt>d</dt>
<dd>data, accepts a NONMEM style data frame for 1 subject with columns for TIME, AMT,MDV,RATE, RATEALL, DV, CL, V1, Q12, V2, Q13, V3, CLM,VM,km</dd></dl>

Arguments

3-compartment IV infusion with first-order metabolite formation — ThreeCompIVinfusionMetab

<dl>

<dt>d</dt>
<dd>data, accepts a NONMEM style data frame for 1 subject with columns for TIME, AMT,MDV,RATE, RATEALL, DV, CL, V1, Q12, V2, Q13, V3, CLM,VM,km</dd>

</dl>

ThreeCompIVinfusionMetab: 3-compartment IV infusion with first-order metabolite formation

Description

Usage

Value

Arguments