apply_duration_scale

E.g. see Centanni et al. Clin Pharmacokinet 2024. An estimated scaling factor
for the length of the infusion was applied there in a model for vincristine.
This is likely most relevant for very short infusions.

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).

Ron Keizer

PKPDsim

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Jasmine Hughes

Dominic Tong

Kara Woo

Jordan Brooks

InsightRX 

apply_duration_scale function

<dl><dt>regimen</dt>
<dd>PKPDsim regimen</dd>
<dt>duration_scale</dt>
<dd>infusion length scale.</dd>
<dt>parameters</dt>
<dd>parameter list, required if the duration scale is
specified as a parameter.</dd>
<dt>cmt_mapping</dt>
<dd>map of administration types to compartments, e.g.
<code>list("oral" = 1, "infusion" = 2, "bolus" = 2)</code>.</dd></dl>

Arguments

Apply infusion duration scale to a regimen — apply_duration_scale

<dl>

<dt>regimen</dt>
<dd>PKPDsim regimen</dd>


<dt>duration_scale</dt>
<dd>infusion length scale.</dd>


<dt>parameters</dt>
<dd>parameter list, required if the duration scale is
specified as a parameter.</dd>


<dt>cmt_mapping</dt>
<dd>map of administration types to compartments, e.g.
<code>list("oral" = 1, "infusion" = 2, "bolus" = 2)</code>.</dd>

</dl>

apply_duration_scale: Apply infusion duration scale to a regimen

Description

Usage

Value

Arguments

Details