calc_dydP

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).

Ron Keizer

PKPDsim

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Jasmine Hughes

Dominic Tong

Kara Woo

Jordan Brooks

InsightRX 

calc_dydP function

<dl><dt>dy</dt>
<dd>dy</dd>
<dt>y</dt>
<dd>dependent value</dd>
<dt>rel_delta</dt>
<dd>relative delta</dd>
<dt>log_y</dt>
<dd>logical indicating if the dependent variable is log transformed</dd></dl>

Arguments

Calculate derivative — calc_dydP

<dl>

<dt>dy</dt>
<dd>dy</dd>


<dt>y</dt>
<dd>dependent value</dd>


<dt>rel_delta</dt>
<dd>relative delta</dd>


<dt>log_y</dt>
<dd>logical indicating if the dependent variable is log transformed</dd>

</dl>

Calculate derivative

calc_dydP: Calculate derivative

Description

Usage

Arguments