get_t_obs_from_regimen

Extract sensible default observation times from a specified regimen

internal

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).

Ron Keizer

PKPDsim

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Jasmine Hughes

Dominic Tong

Kara Woo

Jordan Brooks

InsightRX 

get_t_obs_from_regimen function

<dl><dt>regimen</dt>
<dd>regimen created using <code>new_regimen()</code></dd>
<dt>obs_step_size</dt>
<dd>step size between observations. Will be auto-calculated if NULL</dd>
<dt>t_max</dt>
<dd>max time value</dd>
<dt>covariates</dt>
<dd>covariates object, created using <code>list(new_covariate(), ...)</code></dd>
<dt>extra_t_obs</dt>
<dd>add timepoints to t_obs at which covariate is changing (<code>T</code>/<code>F</code>)</dd>
<dt>t_init</dt>
<dd>time of initiation of the ODE system. Usually 0.</dd></dl>

Arguments

Extract sensible default observation times from a specified regimen — get_t_obs_from_regimen

<dl>

<dt>regimen</dt>
<dd>regimen created using <code>new_regimen()</code></dd>


<dt>obs_step_size</dt>
<dd>step size between observations. Will be auto-calculated if NULL</dd>


<dt>t_max</dt>
<dd>max time value</dd>


<dt>covariates</dt>
<dd>covariates object, created using <code>list(new_covariate(), ...)</code></dd>


<dt>extra_t_obs</dt>
<dd>add timepoints to t_obs at which covariate is changing (<code>T</code>/<code>F</code>)</dd>


<dt>t_init</dt>
<dd>time of initiation of the ODE system. Usually 0.</dd>

</dl>

get_t_obs_from_regimen: Extract sensible default observation times from a specified regimen

Description

Usage

Arguments