regimen_to_nm

Convert PKPDsim regimen to NONMEM table (doses only)

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).

Ron Keizer

PKPDsim

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Jasmine Hughes

Dominic Tong

Kara Woo

Jordan Brooks

InsightRX 

regimen_to_nm function

<dl><dt>reg</dt>
<dd><code>PKPDsim</code> regimen, created using <code>new_regimen()</code> function</dd>
<dt>dose_cmt</dt>
<dd>dosing compartment, if not specified in <code>reg</code> object</dd>
<dt>n_ind</dt>
<dd>repeat for <code>n_ind</code> subjects</dd>
<dt>t_obs</dt>
<dd>add observation time(s)</dd>
<dt>obs_cmt</dt>
<dd>observation compartment for added observation time(s)</dd>
<dt>bioav</dt>
<dd>bioavailability (numeric vector, can not be a parameter)</dd></dl>

Arguments

Convert PKPDsim regimen to NONMEM table (doses only) — regimen_to_nm

<dl>

<dt>reg</dt>
<dd><code>PKPDsim</code> regimen, created using <code>new_regimen()</code> function</dd>


<dt>dose_cmt</dt>
<dd>dosing compartment, if not specified in <code>reg</code> object</dd>


<dt>n_ind</dt>
<dd>repeat for <code>n_ind</code> subjects</dd>


<dt>t_obs</dt>
<dd>add observation time(s)</dd>


<dt>obs_cmt</dt>
<dd>observation compartment for added observation time(s)</dd>


<dt>bioav</dt>
<dd>bioavailability (numeric vector, can not be a parameter)</dd>

</dl>

regimen_to_nm: Convert PKPDsim regimen to NONMEM table (doses only)

Description

Usage

Value

Arguments