reparametrize

Mostly useful for reparametrizing models into standard parametrizations, e.g. to
NONMEM TRANS or clinPK parametrizations.

Simulate dose regimens for pharmacokinetic-pharmacodynamic (PK-PD)
models described by differential equation (DE) systems. Simulation using
ADVAN-style analytical equations is also supported (Abuhelwa et al. (2015)
<doi:10.1016/j.vascn.2015.03.004>).

Ron Keizer

PKPDsim

Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations

Jasmine Hughes

Dominic Tong

Kara Woo

Jordan Brooks

InsightRX 

reparametrize function

<dl><dt>model</dt>
<dd>PKPDsim model, compiled using <code>reparametrization</code> argument or in metadata object.</dd>
<dt>parameters</dt>
<dd>list of model parameters</dd>
<dt>covariates</dt>
<dd>covariates list, specified as PKPDsim covariates</dd></dl>

Arguments

Reparametrize model parameters using a reparametrization defined within the model. — reparametrize

<dl>

<dt>model</dt>
<dd>PKPDsim model, compiled using <code>reparametrization</code> argument or in metadata object.</dd>


<dt>parameters</dt>
<dd>list of model parameters</dd>


<dt>covariates</dt>
<dd>covariates list, specified as PKPDsim covariates</dd>

</dl>

reparametrize: Reparametrize model parameters using a reparametrization defined within the model.

Description

Usage

Value

Arguments