estim_lloq

Estimate LLOQ From Existing Additive and Proportional errors

Automate pharmacokinetic/pharmacodynamic bioanalytical procedures based on best practices and regulatory recommendations.
The package impose regulatory constrains and sanity checking for common bioanalytical procedures.
Additionally, 'PKbioanalysis' provides a relational infrastructure for plate management and injection sequence.

Omar Elashkar

PKbioanalysis

Pharmacokinetic Bioanalysis Experiments Design and Exploration

estim_lloq function

<dl><dt>add_err</dt>
<dd>Additive error (constant)</dd>
<dt>prop_err</dt>
<dd>Proportional error (CV)</dd>
<dt>cv_lloq</dt>
<dd>Maximum coefficient of variation at LLOQ</dd>
<dt>cv_lqc</dt>
<dd>Maximum coefficient of variation at LQC
A method to estimate LLOQ from existing additive and proportional errors. The function does inequality constrained optimization to find the LLOQ.</dd></dl>

Arguments

Author

Estimate LLOQ From Existing Additive and Proportional errors — estim_lloq

<dl>

<dt>add_err</dt>
<dd>Additive error (constant)</dd>


<dt>prop_err</dt>
<dd>Proportional error (CV)</dd>


<dt>cv_lloq</dt>
<dd>Maximum coefficient of variation at LLOQ</dd>


<dt>cv_lqc</dt>
<dd>Maximum coefficient of variation at LQC
A method to estimate LLOQ from existing additive and proportional errors. The function does inequality constrained optimization to find the LLOQ.</dd>

</dl>

estim_lloq: Estimate LLOQ From Existing Additive and Proportional errors

Description

Usage

Arguments

Author