datasets

We innovatively defined a pathway mutation accumulate perturbation score (PMAPscore) to reflect the position and the cumulative effect of the genetic mutations at the pathway level. Based on the PMAPscore of pathways, identified prognosis-related pathways altered by somatic mutation and predict immunotherapy efficacy by constructing a multiple-pathway-based risk model (Tarca, Adi Laurentiu et al (2008) <doi:10.1093/bioinformatics/btn577>).

Junwei Han

PMAPscore

Identify Prognosis-Related Pathways Altered by Somatic Mutation

Yalan He

Xiangmei Li

sig function

<p>An object of class <code>character</code> of length 7.</p>

sig: sig

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