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PRIMEplus (version 1.0.16)

Study Design for Immunotherapy Clinical Trials

Description

Perform sample size, power calculation and subsequent analysis for Immuno-oncology (IO) trials composed of responders and non-responders.

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Version

Install

install.packages('PRIMEplus')

Monthly Downloads

125

Version

1.0.16

License

GPL-2

Maintainer

Bill Wheeler

Last Published

January 10th, 2024

Functions in PRIMEplus (1.0.16)

getHazard

Compute initial estimates for the baseline hazard
data

Data for examples
PRIMEplus.SampleSize

Sample Size
generate_data

Simulated data
PRIMEplus.ReRand.LRT

Randomization Test
PRIMEplus.Power

Power
PRIMEplus-package

Study design for immunotherapy clinical trials
PRIMEplus.LRT

Likelihood Ratio Test
PRIMEplus.EM

EM algorithm