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PSCBS (version 0.45.1)

callAllelicBalanceByDH.PairedPSCBS: Calls segments that are in allelic balance

Description

Calls segments that are in allelic balance by thresholding on DH using a predetermined threshold. The variability of the DH mean levels is taken into account via a bootstrap estimator.

Usage

## S3 method for class 'PairedPSCBS':
callAllelicBalanceByDH(fit, delta=estimateDeltaAB(fit, flavor = "qq(DH)"), alpha=0.05,
  ..., verbose=FALSE)

Arguments

flavor
A character string specifying which type of call to use.
delta
(Tuning parameter) A non-negative numeric threshold.
alpha
A numeric in [0,1] specifying the upper and lower quantiles calculated by the bootstrap estimator.
...
Additional arguments passed to the bootstrap estimator *bootstrapTCNandDHByRegion().

Value

  • Returns a PairedPSCBS object with allelic-balance calls.

Algorithm

  • Foo
  • Bar

See Also

Instead of calling this method explicitly, it is recommended to use the *callAllelicBalance() method.