PWMEnrich (version 4.8.2)

motifRankingForGroup,MotifEnrichmentResults-method: Get a ranking of motifs by their enrichment in the whole set of sequences

Description

Get a ranking of motifs by their enrichment in the whole set of sequences

Arguments

obj

a MotifEnrichmentResults object

bg

if to use background corrected P-values to do the ranking (if available)

id

if to show PWM IDs instead of target TF names

order

if to output the ordering of PWMs instead of actual P-values or raw values

rank

if the output should be rank of a PWM instead of actual P-values or raw values

unique

if TRUE, only the best rank is taken for each TF (only when id = FALSE, order = FALSE)

...

currently unused

Value

a vector of log(P-values), P-values or raw enrichments sorted such that the first motif is most enriched

Examples

if(require("PWMEnrich.Dmelanogaster.background")){
   ###
   # load the pre-compiled lognormal background
   data(PWMLogn.dm3.MotifDb.Dmel)

   # scan two sequences for motif enrichment
   sequences = list(DNAString("GAAGTATCAAGTGACCAGTAAGTCCCAGATGA"), DNAString("AGGTAGATAGAACAGTAGGCAATGAAGCCGATG"))
   res = motifEnrichment(sequences, PWMLogn.dm3.MotifDb.Dmel)

   # most enriched in both sequences (sorted by lognormal background P-value)
   head(motifRankingForGroup(res))

   # Return a non-redundant set of TFs
   head(motifRankingForGroup(res, unique=TRUE))

   # sorted by raw affinity instead of P-value
   head(motifRankingForGroup(res, bg=FALSE))

   # show IDs instead of target TF names
   head(motifRankingForGroup(res, id=TRUE))

   # output the rank instead of P-value
   head(motifRankingForGroup(res, rank=TRUE))
}