KD: To compute the Kyte-Doolittle hydrophobicity index
Description
Hydrophobicity scales are values that define relative hydrophobicity of amino acid residues. These scales are commonly used to predict the transmembrane alpha-helices of membrane proteins. When consecutively measuring amino acids of a protein, changes in value indicate attraction of specific protein regions towards the hydrophobic region inside lipid bilayer. This index is calculated using the scale proposed by Kyte and Dollitle in 1982.
Usage
KD(seq)
Arguments
seq
AA sequence string in upper case
References
Kyte, J., & Doolittle, R. F. (1982). A simple method for displaying the hydropathic character of a protein. Journal of molecular biology, 157(1), 105-132.