Learn R Programming

Peptides (version 0.4)

h: To compute the Eisenberg (1984) hydrophobicity index

Description

Hydrophobicity scales are values that define relative hydrophobicity of amino acid residues. These scales are commonly used to predict the transmembrane alpha-helices of membrane proteins. When consecutively measuring amino acids of a protein, changes in value indicate attraction of specific protein regions towards the hydrophobic region inside lipid bilayer. This index is calculated using the scale proposed by Eisenberg in 1984.

Usage

h(seq)

Arguments

seq
AA sequence string in upper case

References

Eisenberg, David. "Three-dimensional structure of membrane and surface proteins." Annual review of biochemistry 53.1 (1984): 595-623.

Examples

Run this code
# Hydrohobicity index of Urocortin 1
h("DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV")

Run the code above in your browser using DataLab