PhViD.gui: Graphical User Interface for the PhViD package

Description

This function makes possible the use of all the signal detection methods through a friendly user interface. The data have to be in a .csv file, ie with ";" as column separator (see read.table) and must contain the label of the column. The first two columns must be respectively the labels of the drugs and the adverse events. The third column is the number of spontaneous reports corresponding to the couple involved.

Usage

PhViD.gui(dummy = NULL)

Arguments

dummy

No argument is required.

encoding

UTF-8

Details

The GUI is simply called by PhViD.gui().

References

Ahmed I, Dalmasso C, Haramburu F, Thiessard F, Broët{Broet} P, Tubert-Bitter P. False discovery rate estimation for frequentist pharmacovigilance signal detection methods. Biometrics. 2010 Mar;66(1):301-309.

Ahmed I, Haramburu F, Fourrier-Réglat A, Thiessard F, Kreft-Jais C, Miremont-Salamé G, Bégaud B, Tubert-Bitter P. Bayesian pharmacovigilance signal detection methods revisited in a multiple comparison setting. Stat Med. 2009 Jun 15;28(13):1774-1792.

Bate A, Lindquist M, Edwards IR, Olsson S, Orre R, Lansner A, De Freitas RM. A Bayesian Neural Network Method for Adverse Drug Reaction Signal Generation European Journal of Clinical Pharmacology, 1998, 54, 315-321.

Dalmasso C, Broët{Broet} P, Moreau T (2005), A simple procedure for estimating the false discovery rate, Bioinformatics, Bioinformatics, 21: 660 - 668.

DuMouchel W. Bayesian Data Mining in Large Frequency Tables, with an Application to the FDA Spontaneous Reporting System. The American Statistician. 1999, 53. 177-190.

Evans SJ, Waller PC, Davis S, Use of Proportional Reporting Ratios (PRRs) for Signal Generation from Spontaneous Adverse Drug Reaction Reports Pharmacoepidemiology and Drug Safety, 2001, 10, 483-486.

Noren, GN, Bate A, Orre R, Edwards IR, Extending the methods used to screen the WHO drug safety database towards analysis of complex associations and improved accuracy for rare events Statistics in Medicine, 2006, 25, 3740-3757.

van Puijenbroek EP, Bate A, Leufkens HG, Lindquist M, Orre R, Egberts AC, A Comparison of Measures of Disproportionality for Signal Detection in Spontaneous Reporting Systems for Adverse Drug Reactions Pharmacoepidemiology and Drug Safety, 2002, 11, 3-1.