ClinicalTrialCoverage

<code>Population-class</code> object: vaccinated subjects with assigned PoD

vaccinated

<code>Population-class</code> object: control subjects with assigned PoD

control

numeric: value from (0, 1) interval, confidence level of interest

Function works the same way as <code>ClinicalTrial</code> function but it also calculates 80% and 90% confidence intervals.

Set of functions that implement the PoDBAY method, described in the publication 'A method to estimate probability of disease and vaccine efficacy from clinical trial immunogenicity data' by Julie Dudasova, Regina Laube, Chandni Valiathan, Matthew C. Wiener, Ferdous Gheyas, Pavel Fiser, Justina Ivanauskaite, Frank Liu and Jeffrey R. Sachs (NPJ Vaccines, 2021), <doi:10.1038/s41541-021-00377-6>.

Julie Dudasova (MSD)

PoDBAY

Vaccine Efficacy Estimation Package

Pavel Fiser (MSD)

Tomas Bartonek (MSD)

Regina Laube (MSD)

ClinicalTrialCoverage function

Clinical trial function expanded for usage in simulations when the calculation of coverage probability is needed for three confidence intervals: 80%, 90%, and user-defined — ClinicalTrialCoverage

Clinical trial function expanded for usage in simulations when the calculation of coverage probability is needed for three confidence intervals: 80%, 90%, and user-defined

ClinicalTrialCoverage: Clinical trial function expanded for usage in simulations when the calculation of coverage probability is needed for three confidence intervals: 80%, 90%, and user-defined

Description

Usage

Arguments

Value