estimatedParameters

A dataset containing estimated set of PoD curve parameters. (Set of PoD curve parameters is a vector obtained by number of replications specified by repeatCount. These replications are performed for calculation of a confidence interval. For more details, see the supplementary material of the article).

datasets

Set of functions that implement the PoDBAY method, described in the publication 'A method to estimate probability of disease and vaccine efficacy from clinical trial immunogenicity data' by Julie Dudasova, Regina Laube, Chandni Valiathan, Matthew C. Wiener, Ferdous Gheyas, Pavel Fiser, Justina Ivanauskaite, Frank Liu and Jeffrey R. Sachs (NPJ Vaccines, 2021), <doi:10.1038/s41541-021-00377-6>.

Julie Dudasova (MSD)

PoDBAY

Vaccine Efficacy Estimation Package

Pavel Fiser (MSD)

Tomas Bartonek (MSD)

Regina Laube (MSD)

estimatedParameters function

data frame<dl class="dl-horizontal">
 <dt>pmax</dt><dd>pmax: maximum PoD</dd>
 <dt>et50</dt><dd>et50: titer value corresponding to the pmax/2</dd>
 <dt>slope</dt><dd>slope: slope of the PoD curve</dd>
</dl>

Format

Estimated PoD curve parameters — estimatedParameters

data frame<dl class='dl-horizontal'>
 <dt>pmax</dt><dd>pmax: maximum PoD</dd>
 <dt>et50</dt><dd>et50: titer value corresponding to the pmax/2</dd>
 <dt>slope</dt><dd>slope: slope of the PoD curve</dd>
</dl>

estimatedParameters: Estimated PoD curve parameters

Description

Usage

Arguments

Format