This generic function calculates the linkage disequilibrium between regions.
Usage
## S3 method for class 'GENOME':
mult.linkage.stats(object,lower.bound=0,upper.bound=1,pairs=FALSE)
Arguments
object
an object of class "GENOME"
lower.bound
sites with minor-allele-frequency>=lower.bound are considered
upper.bound
sites with minor-allele-frequency
pairs
permutation matrix of pairwise comparisons
Value
The return value is a modified object of class "GENOME"
--------------------------------------------------------------
The following slots will be modified in the "GENOME" object
--------------------------------------------------------------
mult.LinkageSome linkage statistics for each pair of regions (R2, P-value, Distance)
The Fisher-Exact-Test is used to calculate the P-values.
Details
pairs is a matrix. Each column contains the pairwise comparison region IDs.
1 1
2 3
compares region 1 with 2, and region 1 with 3.