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Power2Stage (version 0.5.2)

Power and Sample-Size Distribution of 2-Stage Bioequivalence Studies

Description

Contains functions to obtain the operational characteristics of bioequivalence studies with 2-stage designs (TSD) via simulations.

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install.packages('Power2Stage')

Monthly Downloads

339

Version

0.5.2

License

GPL (>= 2)

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Maintainer

D. Labes

Last Published

April 20th, 2019

Functions in Power2Stage (0.5.2)

sampleN2.TOST

Sample size re-estimation of adaptive 2-stage BE studies in 2x2 crossover and parallel designs based on power of TOST
power.tsd.ssr

Power of 2-stage BE studies in 2x2 crossover designs with interim sample size re-estimation
power.tsd.GS

Power calculation for non-adaptive group sequential (2-stage) BE studies
power.tsd.p

Power calculation of adaptive 2-stage BE studies in 2-group parallel designs
power.tsd.in

Power calculation of adaptive 2-stage BE studies with 2x2 crossover design, based on the Inverse Normal method
power.tsd.KM

Power calculation of adaptive 2-stage BE studies (2x2 crossover) (variant of power.2stage to obtain the results of Karalis / Macheras)
power.tsd.fC

Power calculation of adaptive 2-stage BE studies (2x2 crossover) with a futility criterion for the point estimate of T/R or its 90% CI
power.tsd

Power calculation of adaptive 2-stage BE studies in a 2x2 crossover design
final.tsd.in

Analysis after second stage of 2-stage 2x2 crossover design based on the Inverse Normal method
interim.tsd.in

Interim analysis of first stage data of 2-stage 2x2 crossover designs based on the Inverse Normal method