bib.CL: Design matrices of period balanced incomplete block designs
Description
This function returns the ‘design’ matrix of incomplete
block designs described by Chow & Liu. The design matrices were
recoded 1=R, 2=T1, 3=T2, …
Usage
bib.CL(trt, p)
Arguments
trt
Number of treatments (3 to 5).
p
Number of periods (2 to trt-1).
Value
Matrix containing the sequences in rows and periods in columns.
The entry (i, j) of the matrix corresponds to the treatment or
dose (index) a subject within i-th sequence gets in the
j-th period.
References
Chow SC, Liu JP. Design and Analysis of Bioavailability and Bioequivalence Studies.
Boca Raton: CRC Press; 3 edition 2009. Chapter 2.6.