PowerTOST (version 1.4-9)

ct9.6.2+ct9.6.6: Sample Size Tables for the 2x2x3 Replicate Crossover Design

Description

These data.frames give sample size tables calculated with sampleN.TOST() for the 2<U+00D7>2<U+00D7>3 replicate crossover design (2-treatment 2-sequence 3-period design.

Details

The data.frames can be accessed by their names.

data.frame	Description
ct9.6.2	Additive model, theta1=--0.2, theta2=+0.2 (BE limits 0.80 -- 1.20)
	approximate power via shifted non-central t-distribution
ct9.6.6	Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1)

Attention! CV is se (standard error) of residuals.

References

Chow SC, Liu JP. Design and Analysis of Bioavailability and Bioequivalence Studies. Boca Raton: CRC Press; 3 edition 2009.

Examples

# NOT RUN {
ct9.6.2
ct9.6.6
# }