PowerTOST (version 1.5-2)

ct9.6.4+ct9.6.8: Sample Size Tables for the 2x4x4 Replicate Crossover Design

Description

These data.frames give sample size tables calculated with sampleN.TOST() for the 2<U+00D7>4<U+00D7>4 replicate crossover design (2-treatment 4-sequence 4-period design).

Details

The data.frames can be accessed by their names.

data.frame	Description
ct9.6.4	Additive model, theta1=--0.2, theta2=+0.2 (BE limits 0.80 -- 1.20)
	approximate power via shifted non-central t-distribution
ct9.6.8	Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1)

Attention! CV is se (standard error) of residuals.

References

Chow SC, Liu JP. Design and Analysis of Bioavailability and Bioequivalence Studies. Boca Raton: CRC Press; 3 edition 2009.

Examples

# NOT RUN {
ct9.6.4
ct9.6.8
# }