PowerTOST (version 1.5-6)

ctSJ.VIII.10+ctSJ.VIII.20+ctCW.III: Sample Size Tables for the Parallel Group Design

Description

These data.frames give sample size tables calculated with sampleN.TOST() for the parallel group design (2 groups).

Author

PowerTOST

Details

The data.frames can be accessed by their names.

data.frame	Description
ctSJ.VIII.10	Multiplicative model, theta1=0.9, theta2=1.1111 (1/theta1), target power=90%
	approximate power via non-central t-distribution
ctSJ.VIII.20	Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1), target power=90%
	approximate power via non-central t-distribution
ctCW.III	Additive model, theta1=--0.2, theta2=+0.2 (BE limits 0.80 -- 1.20), exact

Attention! Julious gives sample size per group.

References

Julious SA. Tutorial in Biostatistics. Sample sizes for clinical trials with Normal data. Stat Med. 2004;23(12):1921--86. tools:::Rd_expr_doi("10.1002/sim.1783")

Chow SC, Wang H. On Sample Size Calculation in Bioequivalence Trials. J Pharmacokinet Pharmacodyn. 2001;28(2):155--69. tools:::Rd_expr_doi("10.1023/A:1011503032353")

Examples

ctSJ.VIII.10
ctSJ.VIII.20
ctCW.III