CRRtoRR

Given a vector of cumulative-risk ratios, computes risk ratios

survival

Tools for the evaluation of interim analysis plans for sequentially
monitored trials on a survival endpoint; tools to construct efficacy and
futility boundaries, for deriving power of a sequential design at a specified
alternative, template for evaluating the performance of candidate plans at a
set of time varying alternatives. See Izmirlian, G. (2014) <doi:10.4310/SII.2014.v7.n1.a4>.

Grant Izmirlian

PwrGSD

Power in a Group Sequential Design

CRRtoRR function

<dl> <dt>CRR</dt>
<dd>vector of cumulative risk ratios of length <code>m</code></dd> <dt>DT</dt>
<dd>vector of time increments upon which the cumulative ratios
 represent. For example if the hazard takes values
 <code>h_1, h_2,..., h_m</code> on the intervals <code>[t_1, t_2), [t_2, t_3),
 ..., [t_m, t_{m+1})</code> then <code>DT</code> will be <code>c(t_2-t_1, t_3 -t_2,
 ..., t_{m+1} - t_m)</code></dd> <dt>h</dt>
<dd>The hazard in the reference arm, of length <code>m</code></dd></dl>

Arguments

Grant Izmirlian &lt;izmirlian@nih.gov&gt;

Author

Cumulative-risk ratios to risk ratios — CRRtoRR

<dl>

 <dt>CRR</dt>
<dd>vector of cumulative risk ratios of length <code>m</code></dd>

 <dt>DT</dt>
<dd>vector of time increments upon which the cumulative ratios
 represent. For example if the hazard takes values
 <code>h_1, h_2,..., h_m</code> on the intervals <code>[t_1, t_2), [t_2, t_3),
 ..., [t_m, t_{m+1})</code> then <code>DT</code> will be <code>c(t_2-t_1, t_3 -t_2,
 ..., t_{m+1} - t_m)</code></dd>

 <dt>h</dt>
<dd>The hazard in the reference arm, of length <code>m</code></dd>

</dl>

CRRtoRR: Cumulative-risk ratios to risk ratios

Description

Usage

Value

Arguments

Author

Examples