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QTOCen (version 0.1.1)

Quantile-Optimal Treatment Regimes with Censored Data

Description

Provides methods for estimation of mean- and quantile-optimal treatment regimes from censored data. Specifically, we have developed distinct functions for three types of right censoring for static treatment using quantile criterion: (1) independent/random censoring, (2) treatment-dependent random censoring, and (3) covariates-dependent random censoring. It also includes a function to estimate quantile-optimal dynamic treatment regimes for independent censored data. Finally, this package also includes a simulation data generative model of a dynamic treatment experiment proposed in literature.

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Version

Install

install.packages('QTOCen')

Monthly Downloads

196

Version

0.1.1

License

GPL (>= 2)

Maintainer

Yu Zhou

Last Published

June 4th, 2019

Functions in QTOCen (0.1.1)

Bnk_func

Generate biquadratic kernel weights for a univariate variable
Gene_Mean_CenIPWE

A low-level function for the generic optimization step in estimating Mean-optimal treatment regime for censored data
LocalKM

Kernel-based Local Kaplan-Meier Estimator
IPWE_Qopt_DepCen_general

Estimate Quantile-optimal Treatment Regime for covariates-dependent random censoring data
IPWE_mean_IndCen

Estimate the mean-optimal treatment regime for data with independently censored response
IPWE_Qopt_DTR_IndCen

Function to estimate the two-stage quantile-optimal dynamic treatment regime for censored data: the independent censoring Case
IPWE_Qopt_IndCen

Function to estimate the quantile-optimal treatment regime: the independent censoring Case
Gene_Quantile_CenIPWE

A low-level function for the generic optimization step in estimating Quanilte-optimal treatment regime for censored data
IPWE_Qopt_DepCen_trt

Estimate the Quantile-opt Treatment Regime under the assumption that the censoring time's distribution only depends on treatment level
Gene_Quantile_CenIPWE_DTR

A low-level function for the generic optimization step in estimating dynamic Quanilte-optimal treatment regime for censored data
tauhat_func

Kernel-based Local Kaplan-Meier Estimator for the Conditional Probability of the Survival Time
est_quant_ipwe

Estimate the marginal quantile response of a linear static treatment regime
simJLSDdata

Function to generate simulation data from a sequentially randomized experiment designed in jiang2017estimationQTOCen
est_mean_ipwe

Estimate the marginal mean response of a linear static treatment regime
est_quant_TwoStg_ipwe

Estimate the marginal quantile response of a specific dynamic TR