Usage
write.TUDD(X, score = "", order = 1, ref.init = "baseline", MCID, ref.def = "def1",
death = NA, group = NULL, names.group, sensitivity = TRUE, file = "")
Arguments
X
input data matrix or data frame with a quality of life score. Missing values are inserted as NA
score
vector with the name of the quality of life scores of interest
order
a vector equals to 1 if the deterioration corresponds to a decrease of the score, 2 otherwise
ref.init
the reference score to qualify the deterioration.
By default, ref.init is "baseline", i.e. the reference score is the baseline score.
If ref.init is "best", the best previous quality of life score is the reference score.
If ref.init is "previous", the last previous score is the reference score.
MCID
vector equals to the minimal clinically important difference (MCID). Several MCIDs can be specified
ref.def
the deterioration is definitive 1: if there is no clinically significant improvement as compared to the reference score ("def1"); 2: if the deterioration is also observed at all times following the deterioration ("def1"); 3: or there is no clinically significant improvement as compared to the score qualifying the deterioration ("def3")
death
missing if patients who died without experienced a deterioration are censored at the time of the last QoL score, equals to the name of the death date in the dataframe X otherwise
group
the name of the variable in X corresponding to the treatment arm. Only two groups are allowed.
names.group
the name of each treatment group to print
sensitivity
Boolean equals to TRUE by default. If sensitivity is TRUE, then all sensitivity analyses are performed, integrating patients with no baseline or with no follow up as event, death as event and simultaneously no baseline, no follow and death
file
the name of the csv file to create with the results of the time to deterioration analysis