e.step

A list of dataframes (one for each sample), generated by the Patient_schrodinger_cellularities() function.

Schrod

Coordinates of the clones: a list of numeric vectors (1 per sample), with coordinates between 0 and 1.

centers

weights

Factor to compute the probability: makes transition between the cellularity of the clone and the frequency observed

adj.factor

E-Step

Using HTS data, clusters mutations in order to recreate putative
clones from the data provided. It requires genotype at the location of the
variant as well as the depth of coverage and number of reads supporting the
mutation. Additional information may be provided, such as the contamination
in the tumor sample. This package also provides a function QuantumCat() which
simulates data obtained from tumor sequencing.

e.step: Expectation step calculation

Description

Usage

Arguments