RBesT (version 1.6-3)

AS: Ankylosing Spondylitis.

Description

Data set containing historical information for placebo for a phase II trial of ankylosing spondylitis patients. The primary efficacy endpoint was the percentage of patients with a 20 according to the Assessment of SpondyloArthritis international Society criteria for improvement (ASAS20) at week 6.

Usage

AS

Format

A data frame with 8 rows and 3 variables:

study

study

n

study size

r

number of events

References

Baeten D. et. al, The Lancet, 2013, (382), 9906, p 1705

Examples

## Setting up dummy sampling for fast execution of example
## Please use 4 chains and 20x more warmup & iter in practice
.user_mc_options <- options(RBesT.MC.warmup=50, RBesT.MC.iter=100,
                            RBesT.MC.chains=2, RBesT.MC.thin=1)

set.seed(34563)
map_AS <- gMAP(cbind(r, n-r) ~ 1 | study,
               family=binomial,
               data=AS,
               tau.dist="HalfNormal", tau.prior=1,
               beta.prior=2)
## Recover user set sampling defaults
options(.user_mc_options)