This data set contains 18 columns of protein expression values measured in 214 early monocyte cells using mass cytometry (CyTOF).
data(cytof)Note that there are three distinct objects included in the data
set: AML10.node287, AML10,node287.rips, and Arip.
AML10.node287A numerical data matrix with 214 rows (single cells) amd 18 columns (antibody-protein markers). Values were obtained using mass cytometry applied to a sample collected from a patient with acute myeloid leukemia (AML).
AML10.node287.ripsThis object is a
"Rips diagram". It was produced by running the
ripsDiag function from the TDA R
package on the AML10.node287 data matrix.
AripThis object is a "Rips diagram". It was produced
by running the ripsDiag function from the
TDA R package on the Euclidean distance matrix
between the single cells.
Kevin R. Coombes krc@silicovore.com, RB McGee mcgee@sholycross.edu, Jake Reed hreed@augusta.edu
Behbehani GK, Samusik N, Bjornson ZB, Fantl WJ, Medeiros BC, Nolan GP. Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy. Cancer Discov. 2015 Sep;5(9):988-1003. doi: 10.1158/2159-8290.CD-15-0298.