RTN.data: A pre-processed dataset for the RTN package.
Description
A minimum dataset used to demonstrate RTN main functions.
Format
dt4rtn List containing 6 R objects: 'gexp', 'gexpIDs', 'pheno', 'phenoIDs', 'hits' and 'tfs'.Details
The dataset consists of 6 R objects used in the RTN vignettes. It should be regarded as a toy example for demonstration purposes only, despite being extracted, pre-processed and size-reduced from Fletcher et al. (2012) and Curtis et al. (2012).
- dt4rtn$gexp
- a named gene expression matrix with 50 samples (reduced for demonstration purposes only).
dt4rtn$gexpIDsa data.frame of characters with probe ids matching a secundary annotation source (e.g. Probe-to-ENTREZ).
dt4rtn$phenoa named numeric vector with differential gene expression data.
dt4rtn$phenoIDsa data.frame of characters with probe ids matching a secundary annotation source (e.g. Probe-to-ENTREZ).
dt4rtn$hitsa character vector with genes differentially expressed.
dt4rtn$tfsa named vector with transcriptions factors.References
Fletcher M.N.C. et al., Master regulators of FGFR2 signalling and breast cancer risk. Journal Paper (in preparation), 2012.Curtis C. et al., The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 486, 7403. 2012.