RUVnormalize (version 1.6.0)

RUV for normalization of expression array data

Description

RUVnormalize is meant to remove unwanted variation from gene expression data when the factor of interest is not defined, e.g., to clean up a dataset for general use or to do any kind of unsupervised analysis.

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Version

1.6.0

License

GPL-3

Maintainer

Laurent Jacob

Last Published

February 15th, 2017

Functions in RUVnormalize (1.6.0)

naiveReplicateRUV

Remove unwanted variation from a gene expression matrix using replicate samples

naiveRandRUV

Remove unwanted variation from a gene expression matrix using negative control genes

svdPlot

Plot the data projected into the space spanned by their first two principal components

clScore

Computes a distance between two partitions of the same data

iterativeRUV

Remove unwanted variation from a gene expression matrix using control genes, optionally replicate samples, and iterative estimates of the factor of interest