hbd1

<p>The results were obtained by running the a model with 4 layers and the predhbd
function for all HBD classes. Results were extracted for chromosome 1.</p>

datasets

Functions to identify Homozygous-by-Descent (HBD) segments associated with runs of homozygosity (ROH) and to
estimate individual autozygosity (or inbreeding coefficient). HBD segments and autozygosity are assigned to multiple HBD classes
with a model-based approach relying on a mixture of exponential distributions. The rate of the exponential distribution is distinct
for each HBD class and defines the expected length of the HBD segments. These HBD classes are therefore related to the age of the
segments (longer segments and smaller rates for recent autozygosity / recent common ancestor). The functions allow to estimate the
parameters of the model (rates of the exponential distributions, mixing proportions), to estimate global and local autozygosity
probabilities and to identify HBD segments with the Viterbi decoding. The method is fully described in Druet and Gautier (2017)
<doi:10.1111/mec.14324> and Druet and Gautier (2022) <doi:10.1016/j.tpb.2022.03.001>.

Tom Druet

RZooRoH

Partitioning of Individual Autozygosity into Multiple
Homozygous-by-Descent Classes

Naveen Kumar Kadri

Amandine Bertrand

Mathieu Gautier

hbd1 function

Format

The result of local IBD probabilities for a pair of individuals among the 18
cows from the Amsterdam Island. — hbd1

The result of local IBD probabilities for a pair of individuals among the 18
cows from the Amsterdam Island.

hbd1: The result of local IBD probabilities for a pair of individuals among the 18 cows from the Amsterdam Island.

Description

Usage

Arguments

Format

Details