LQE: Linear Quadratic Extrapolated (LQE) Dose Conversion
Description
This function and its associated methods calculate LQE-weighted dose(s) for a given DVH or DVH.list object, allowing iso-effect conversion between one or more DVH(s) employing different dose fractionation.
Usage
## S3 method for class 'DVH,numeric':
LQE(x, aB, fractions = NULL, dose.units = c("cGy", "Gy"))
## S3 method for class 'DVH.list,numeric':
LQE(x, aB, fractions = NULL, dose.units = NULL)
## S3 method for class 'numeric,numeric':
LQE(x, aB, fractions = NULL)
Arguments
x
Can represent either numeric value(s) or otherwise an object of class DVH or DVH.list for which to calculate LQE value(s).
aB
Numeric value specifying tissue-specific parameter "alpha/beta ratio". Multiple values may be specified for LQE conversion of x, where x is a DVH.list object containing multiple DVH objects.
fractions
Numeric value specifying the number of fractions in which doses are deposited. Multiple values may be specified for LQE conversion of x, where x is a DVH.list object containing multiple DVH objects. Two
dose.units
Value specifying dose units (must be one of "cGy" or "Gy"). Multiple values may be specified for LQE conversion of x, where x is a DVH.list object containing multiple DVH object
Value
Returns a DVH or DVH.list object, corresponding to original input type for parameter x.
References
Barendsen, G.W. (1982)
Dose fractionation, dose-rate and iso-effect relationships for normal-tissue response.
Int J Radiat Oncol Biol Phys8(11):1981-1997.